![]() Step 3. In the "Print" dialog box, select "Microsoft Print to PDF" as the printer and click on the "Print" button. Step 2. Click on the three dots (.) in the top-right corner of the screen to open the menu, and then select "Print" from the options. Step 1. Open the PDF file you want to convert in Microsoft Edge. Here, you will know how to use Microsoft Edge to convert PDF to Word offline for free, along with some tips and tricks to ensure the best results. Microsoft Edge is a web browser that comes pre-installed on Windows 10, and it includes a range of features, including a built-in PDF reader and editor. If you're a Windows 10 user, you may be surprise that you can also use Microsoft Edge to convert PDF to Word offline free. How to Convert PDF to Word Offline Free with Microsoft Edge Most commonly, they are placed in the wrong place in the resulting Word document. However, some non-text objects such as images or tables may not be converted accurately when using this method. Step 4. Reformat the document as necessary and save it as a Word document. If a dialog box appears indicating that reformatting may occur, click "OK." If the document opens in Protected View, click "Enable Content" and then click "OK" again. Step 3. Double-click the PDF file and it will open in Word. Step 2. Select "Open" and navigate to the location of the PDF file. Step 1. Open Microsoft Word and click on the "File" tab. Here's how you can convert PDF to Word offline free using Microsoft Word: Microsoft Word is a popular and widely used word processing application that can also be used to convert PDF files to editable Word documents, without the need for any additional software or online tools. In addition to the already discussed offline PDF to Word converting tools, there's another option you might have at your disposal: Microsoft Word. ![]() How to Convert PDF to Word Offline Free with Microsoft Word Download iTop PDF by clicking the Download button. Now, take a closer look at how to convert PDF to Word offline with iTop PDF. Plus, the user-friendly interface makes the conversion process simple and straightforward. That is, it can convert PDF without any loss of formatting or quality.ġ00% Free and Simple: With iTop PDF, you can convert PDF to Word offline for free, without any need for an internet connection. The converted Word document looks exactly like the original PDF. No Formatting Loss: Not only does iTop PDF promises the quantity of the PDF files you want to convert, but also the quality of the converted files. It utilizes OCR (Optical Character Recognition) technology that can recognize text from scanned PDF files and convert them to editable Word documents. OCR Option Supported: If you are worrying about how to make a scanned PDF editable, this powerful PDF editor comes as your saver. Whether you need to convert a single PDF file or multiple files at once, iTop PDF can make it well done. Add e-signature effortlessly to your PDFįlexible in PDF Converting: There is no limitation on the number of PDF files you want to convert.Split and Merge PDF files easily and quickly.Convert PDF to any format in high quality.What makes iTop PDF a must-have software? ![]()
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![]() ![]() Next turn I was told the elemental was no longer under my control. Cael's roll resulted in "spell affects random target in range" and the Sacred Flame ended up descending on the elemental, which passed their Dex save easily, taking no damage. The result of the roll determines the result of the spell as per a table of various effects. Whenever a spell is cast the caster must roll a d100 and add a modifier. Due to setting conditions in our game magic is presently unreliable. I was not RPing the 'verbal commands' requirement of the spell, to be honest, I think both the DM and I forgot about that aspect, but I had control of the creature's token and was moving/attacking/rolling for the elemental.Ĭael, the cleric, attempted to cast Sacred Flame on one of the Minotaurs. We were fighting about half a dozen Minotaurs in a relatively small room. Mulland cast Conjure Elemental about a minute before going into combat. It was also the first time my wizard Mulland successfully cast the spell Conjure Elemental, so it was a new thing, and when we started playing about 15 months ago we were all relatively new to 5e. That said, my DM has stated that they are trying to run the game as close to RAI as possible. First off, I want to be clear that I understand what the DM says goes & they are the final word on any rules in the game. If this is the case, would the attack that triggered this have to be intentional, or could it also be triggered by an unintentional attack? RAW also seems to suggest that upon receiving a command from the caster the elemental would cease its attack on the companion in question. If the Elemental is issued no commands and is attacked by a companion of the caster RAW seems to suggest that the Elemental could attack the companion which attacked it. Lose control of the elemental, it becomes hostile toward you and your If yourĬoncentration is broken, the elemental doesn’t disappear. ![]() If you don’t issue any commands to the elemental, it defends itselfįrom hostile creatures but otherwise takes no actions. The spell description has two scenarios by which a conjured elemental might take hostile actions against the caster and their companions, one which requires the caster's concentration being broken: ![]() The spell ends if concentration is broken or ended, or if the Elemental reaches 0 HP. The spell's duration is "Concentration, Up to 1 hour". The elemental is friendly to you and your companions for the Duration. If "Yes", under what conditions can this happen?Ĭonjure Elemental is a D&D 5e spell available to Wizards and Druids and can be found on p. ![]() ![]() plyr-audio-range-thumb-active-shadow-color The color of the shadow when the video scrubber handle/thumb is :active (pressed). plyr-video-range-thumb-active-shadow-color The height of the scrubber/progress track. The width of the shadow when the scrubber handle/thumb is :active (pressed). The fill color for the buffer indication in the scrubber for audio. The fill color for the buffer indication in the scrubber for video. The background color on the loading state in the scrubber. The size of the stripes in the loading state in the scrubber. The shadow below the border of the back button in the top of the sub menu pages. The border color for the bottom of the back button in the top of the sub menu pages. The size of the arrow on the bottom of the menu. ![]() The text/icon color used when audio controls are :hover, :focus and :focus-visible (equivalent). The background color used when video controls are :hover, :focus and :focus-visible (equivalent). The text/icon color used when video controls are :hover, :focus and :focus-visible (equivalent). ![]() The background color used for checked menu items. The space between controls (sometimes used in a multiple - e.g. The size of the icons used in the controls. The color for the background of captions. The background color for badges in the menu. The color used for the focus styles when an element is :focus-visible (keyboard focused). The background color of video and poster wrappers for using alpha channel videos and poster images. Here's a list of the properties and what they are used for: Name If you want to change any design tokens used for the rendering of the player, you can do so using CSS Custom Properties. If you do not wish to use Vi, you can set your own ads.tagUrl option. Enable ads in the config options and enter your publisher IDĪny questions regarding the ads can be sent straight to vi.ai and any issues with rendering raised through GitHub issues.Grab your publisher ID from the code snippet.Plyr has partnered up with vi.ai to offer monetization options for your videos. Build the project yourself using npm i & npm run build, which installs the dependencies and spits out a build to dist.Download the files from unpkg or similar services.Download the files from the CDN links above, they're already minified.If you don't want to create a build system to include Plyr as an npm module, you can use the pre-built files. Reference, the CDN hosted SVG sprite can be found at. The SVG sprite is loaded automatically from our CDN (provided by Cloudflare). Plyr extends upon the standard HTML5 media element markup so that's all you need for those types. For Streaming we also have example integrations with: Dash.js, Hls.js and Shaka Player Quick setup HTML You can try Plyr in Codepen using our minimal templates: HTML5 video, HTML5 audio, YouTube, Vimeo. □♀️ Sass - to include in your build processes.□ No frameworks - written in "vanilla" ES6 JavaScript, no jQuery required.□ Preview thumbnails - support for displaying preview thumbnails.□ i18n support - support for internationalization of controls.□ Multiple captions - support for multiple caption tracks.□ Speed controls - adjust speed on the fly.□ Playsinline - supports the playsinline attribute.□ Picture-in-Picture - supports picture-in-picture mode.⌨️ Shortcuts - supports keyboard shortcuts.□ Fullscreen - supports native fullscreen with fallback to "full window" modes.□ Events - no messing around with Vimeo and YouTube APIs, all events are standardized across formats.□ API - toggle playback, volume, seeking, and more through a standardized API.□ Streaming - support for hls.js, Shaka and dash.js streaming playback.□ Monetization - make money from your videos.□ Responsive - works with any screen size.for volume and for progress and well, s for buttons. □ Clean HTML - uses the right elements.□ Customizable - make the player look how you want with the markup you want.□ Accessible - full support for VTT captions and screen readers.□ HTML Video & Audio, YouTube & Vimeo - support for the major formats. ![]() ![]() Plyr is a simple, lightweight, accessible and customizable HTML5, YouTube and Vimeo media player that supports modern browsers. ![]() ![]() ![]() Clearly the Nets were banking on Philadelphia having an off day shooting from beyond the arc, but that's not what happened. During the regular season, the Sixers generated the eighth-most wide open 3-pointers in the league, and ranked fifth in knocking them down at a 41.1% clip. Not only that but many of the Sixers' 3-pointers were on wide open attempts on Saturday, due to the Nets doubling Embiid. ![]() Brooklyn's gameplan of forcing the ball out of Embiid's hands and daring everyone else to beat them worked for about five minutes in the first quarter, but then that tactic crumbled rather quickly.It was an interesting tactic from Jacque Vaughn and the Nets staff, given that the Sixers led the league during the regular season in 3-point percentage (38.7%). It was a testament to how scorching hot the team was from deep, and also a result from the Nets double-teaming Joel Embiid for most of the game. What's even more impressive about that number is that the Sixers broke the previous record of 18 before the fourth quarter even started. In Philadelphia's 121-101 win Saturday afternoon, the team connected on 21 shots from 3-point territory, which set a franchise record for most 3s in a playoff game. Eastern Conference playoff scoresĬBS Sports will have live updates throughout the day, keeping track of the latest playoff action with highlights, analysis and more. The full 2023 NBA playoff bracket can be viewed here. James Harden connected on seven of those triples in a 23-point, 13-assist effort, while Joel Embiid added a relatively quiet 26 points. The 76ers started off the day by hitting a franchise record 21 3-pointers in their 121-101 win over the Brooklyn Nets in Game 1. Hawks star Trae Young was held to 16 points on 5-of-18 shooting. Boston's Jaylen Brown led all scorers with 29 points, while Jayson Tatum added 25. The second-seeded Celtics took down the seventh-seeded Atlanta Hawks, racing out to a 30-point halftime lead before holding on for a 112-99 win. Despite a late run by the Cavaliers, led by Donovan Mitchell, the Knicks were able to hold on for a 101-97 victory to steal Game 1 on the road. ET with the Cavaliers hosting the Knicks in the first playoff game in Cleveland without LeBron James since 1998. The third game of the day tipped after 6 p.m. Things wrap up Saturday with the lone Western Conference Game 1 on Saturday as the Kings host the Warriors in the first playoff game in Sacramento since 2006. The 2023 NBA playoffs kicked off Saturday, with the Boston Celtics and New York Knicks joining the Philadelphia 76ers in the win column. ![]() ![]() * WHERE.Matagorda Islands, Brazoria Islands, Galveston Island and Bolivar Peninsula. Nighttime temperatures will offer little reprieve, with lows dropping only to around 80 humid degrees. ![]() HIGH RIP CURRENT RISK IN EFFECT THROUGH THIS EVENING. High pressure is dominating our weather, and this will mean mostly sunny skies, highs near 100 degrees, and southerly winds varying from 5 mph to 15 mph. * IMPACTS.Hot temperatures and high humidity may cause heat More * WHERE.Coastal Jackson, Coastal Matagorda, Matagorda Islands and Brazoria Islands Counties. HEAT ADVISORY REMAINS IN EFFECT UNTIL 8 PM CDT THIS EVENING. Preprints, 16th Radar Meteorology Conf, Houston, Amer. * WHERE.Portions of south central and southeast Texas. (Chapter 13) Fetter, R.W., 1970: Radar weather performance enhanced by pulse compression. * WHAT.Dangerously hot conditions with heat index values up to 117. NWS Forecast Office Houston/Galveston, TX Houston Hobby Airport, 21:53, Mostly Cloudy, 10, 84 Sugar Land, 22:07, Mostly Cloudy, 10, 84 Wharton, 22:15. EXCESSIVE HEAT WARNING REMAINS IN EFFECT UNTIL 8 PM CDT THIS EVENING. Residents with outdoor activities planned are urged to drink plenty of water, More The combination of warm temperatures and high dewpoints will produce heat indices between 105 and 109 degrees across the barrier islands north of Port Aransas today. HEAT INDEX VALUES BETWEEN 105 AND 109 DEGREES ARE EXPECTED TODAY. Houston, TX Weather Forecast and Conditions - The Weather Channel Get more weather bells n’ whistles. * WHERE.Coastal Aransas, Coastal San Patricio, Coastal Refugio, Coastal Calhoun, Kleberg Islands and Nueces Islands Counties. Houston ( Hobby ) Establish a second ground. See a real view of Earth from space, providing a detailed view of. See a real view of Earth from space, providing a detailed view of clouds, weather. Virginia Burlington ( cost Establish two additional radar positions Dallas / Ft. Current and future radar maps for assessing areas of precipitation, type, and intensity. * WHAT.Heat index values up to 114 expected. Current and future radar maps for assessing areas of precipitation, type, and intensity. HEAT ADVISORY REMAINS IN EFFECT FROM NOON TODAY TO 7 PM CDT THIS EVENING. ![]() ![]() * WHEN.From noon today to 7 PM CDT this evening. * WHAT.Dangerously hot conditions with heat index values up to 121 expected. EXCESSIVE HEAT WARNING REMAINS IN EFFECT FROM NOON TODAY TO 7 PM CDT THIS EVENING. ![]() ![]() ![]() The Ultimate Guide to Customizing Your iPhone's Home Screen Without JailbreakingĬustomize Shortcut Icons for Contacts, Playlists, & More on Your iPhone's Home Screen How to Add an Extra Application to Your iPhone or iPad Dock Just redo this step and create a new image, making sure to crop it properly based on what went wrong before. If the icon doesn't look quite right, don't worry. In our case, that's " TikTok." For the last part, tap "Add" in the top right, and the shortcut will pop up on your home screen. ) in the top right, then choose "Add to Home Screen." Here, select the default icon next to the shortcut's name, then tap "Choose Photo." Now, find your icon from Step 1, crop if needed, and tap "Choose." Next, type in a new name for it.Next, choose "(+) Add Action," then "Scripting," followed by "Open App." Select "Choose" in the Scripting card, then find and tap the app you want to tie this shortcut to on your iPhone. ![]() (On iOS 13 and under, you could also tap the "Create Shortcut" card in "My Shortcuts"). To start, you can long-press the Shortcuts app icon on the home screen, then tap "Create Shortcut," or you can open Shortcuts yourself, tap the "My Shortcuts" tab, then tap the plus (+) icon in the top right. With your icon image saved, you're ready to create the shortcut. If not, don't worry, we'll go over cropping later. If you want to save a little time, you can try cropping the image into an icon-sized file at the same time. You can also screenshot an image instead of downloading it. From the quick actions menu, select "Add to Photos." Any image from pretty much any source will work as long as it looks like it could be an icon, it's square or square with rounded corners, or it's an actual icon picture. Search for a picture, tap on a high-quality result, then long-press the image. Really, you could get an image from anywhere - you're favorite comic book, your own photos, a movie still, art sites - without having to worry about copyrights since it'll only be for your use on your iPhone and nowhere else. If you're looking for inspiration, you can always head to Google Images or a stock image site like Pexels or Pixabay. Very simply, you just need to make sure the image you want is saved on your iPhone in some way. That said, there isn't just one way to grab an image for it, and here are a few options to do so: Option 1: Download an Image Yourself If you're reading this article, chances are you have an idea of what you'd like your new app icon to be. More Info: How to Use the Shortcuts App on Your iPhone.The only difference now in iOS 14 is that you can more effectively hide the real app in one of two ways. So, you could change app icons in iOS 12 and iOS 13. An update in late-2018 fixed most of the issues so that all apps were supported. It has been a part of the Shortcuts app since iOS 12 was released, albeit, with limited support. Then, we'll hide the main app out of sight so that it looks like our shortcut is the only version of it.Īfter the release of iOS 14, users discovered this feature, and it started going viral shortly after. That first "app" is the one we'll see on the home screen - the one that uses whichever icon we want. Even if apps with their own app icon options, they may not be what you want, and you can still get new ones via Shortcuts.įor this guide, we're using a shortcut to create one "app" that opens another app. So we have to turn to the Shortcuts app, a built-in Apple tool, to change apps without their own options. There is no feature in the Settings app to change app icons unless an app itself offers up different images to choose from. ![]()
![]() Find out the GTX 660 equivalent, with a review of specifications, price, GTX 660 framerate comparison, GTX 660 rank, and CPU bottlenecks. Maybe swapping out the crunchy options for a couple more acoustic models would have made it even more useful, but this remains an appealing six-string multi-tool and a genuine problem-solver for many gigging players. GTX 660 benchmark with i7-920 at Ultra Quality settings in 82 games and fps benchmarks in 1080p, 1440p, and 4K. “The launch of the Acoustasonic Player Telecaster feels like a no-brainer move for Fender, spreading the potential appeal of what is virtually a whole new category of guitar. The feel of the bevelled arm rest and fingerboard edges says quality and comfort this is an inviting guitar and that Modern Deep-C neck will feel familiar to anyone who has played the electric Player series models.” Graphics Card: Nvidia GeForce GTX 1060 6GB or AMD Radeon RX 580 8GB. A lovely dark rosewood fingerboard and bridge replaces the US version’s ebony, but that’s not anissue for us. OS: Windows 10 (64 bit) Processor: Intel Core i5-9600K or AMD Ryzen 5 2600X. “In terms of feel and build, we honestly can’t find a compromise between this Ensenada-made Player and the US Acoustasonics we’ve tried. MusicRadar: The onboard voice options might have been scaled down but the Acoustasonic Telecaster sticks the landing as a Player Series model, in what could be one of the guitars to make the hybrid build truly go mainstream.įender Player Series Acoustasonic Telecaster: The web says That, in sum, is the sort of thing the Acoustasonic format encourages. That said, it can be pressed into service of many different kinds of styles, perhaps some that are all your own. It is warmer, with a little more width than you’d expect from a Tele’s bridge pickup. Fender promises twang but this isn’t Pete Anderson levels of twang. SkillBench (space shooter) tests user input accuracy. RAM tests include: single/multi core bandwidth and latency. Drive tests include: read, write, sustained write and mixed IO. GPU tests include: six 3D game simulations. ![]() CPU tests include: integer, floating and string. Park yourself on position one for a more traditional electric guitar experience, but don’t necessarily expect a traditional Telecaster experience. How it works - Download and run UserBenchmark. In a sense, this is a sound that almost exists outside of the spectrum of acoustic/electric tones, and is sure to support pedalboard experimentation. NVIDIA’s standard voltage remains at 1.175v, the same as we. GTX 660 is designed to come in between GTX 660 Ti and GTX 650 (also launching. Stopping to take a quick look at voltages, even with a new GPU nothing has changed. The sound is just coming from the piezo and as you turn the blend control it adds drive. GK106’s launch vehicle will be the GeForce GTX 660, the central member of NVIDIA’s mainstream video card lineup. Here is where the true hybrid tones are, and as such, there are fewer references for what we are hearing. PassMark Software has delved into the millions of benchmark results that PerformanceTest users have posted to its web site and produced four charts to help compare the relative performance of different video cards (less frequently known as graphics accelerator cards or display adapters) from major manufacturers such as AMD, nVidia, Intel and others. Both feature identical 28nm NVIDIA Kepler GK104 graphics processors. All of these cards are very power efficient compared to what we were using just several years ago.The Lo-Fi voicings are interesting. To the surprise of many, the GeForce GTX 670 and GTX 660 Ti are nearly the same card. Average Bench: 19.9 (204 th of 701) Based on 123,956 user benchmarks. Taking the average of four games gave the MSI GeFoce GTX 660 OC an average power consumption 9 Watts lower than the EVGA counterpart which averaged 299 Watts. During our Furmark runs, the MSI GeForce GTX 660 OC pulled 296 Watts while the EVGA GeForce GTX 660 SC was pulling 298 Watts. It isn’t a huge difference though and is partly due to the fact that its clock speeds are lower (lower voltages) and the custom PCB design that features a different PWM setup. Power Consumption Results: The MSI GeForce GTX 660 OC managed to pull slightly less power than the EVGA GeForce GTX 660 SC during our gaming and Furmark testing. ![]() We also ran four game titles at 1920×1080 and averaged the peak results recorded the highest Wattage seen on the meter for the gaming results. The OpenGL benchmark FurMark 1.10.1 at 1024×768 resolution. Numbers we measured the peak wattage used by the system while running To idle on the desktop for 15 minutes and took the reading. For testing power consumption, we took our test system and plugged it ![]() ![]() ![]() There are two ways to run the Pacman Retrospective Format. ![]() You’ll also want to bring aspects of your company culture into the meeting, and ensure that your retros are becoming as productive as possible. On that same note, the results of the Retrospective (new insights and goals) are also most effective when put into motion soon after the meeting. Feedback has to be relevant and thorough, which is easiest if it's recalled soon after the experience. ![]() The Pacman Retrospective Format is best suited for reflection periods directly after an Iteration/Sprint culminates. By completing this retrospective, as happens when your team completes any retrospective, you should be able to see marked improvements in software development, morale and teamwork around your company. It involves the Pacman himself, the ghosts, the energy pellets, the remaining lives icon, the high score counter, and the fruits to signify similar aspects of the team's last project. Each element represents a different question in focus, which then gets answered by each team member. The Pacman Retrospective Format uses elements from the Pacman video game to thematically highlight different talking points about the last Iteration/Sprint. The Pacman Retrospective Agile Format will help you put the retro back in Retrospective, and is so quick and easy you’ll be seeing results before you can even say, "Waka Waka.” So why not get into the spirit, gather your team and confront the ghosts-of-Sprints-past! What Is the Pacman Retrospective Format? ![]() ![]() ![]() Que vous soyez novice ou expert, vous saurez rapidement vous adapter à son. FinalCut Pro : montage vido, effets, transitions et export vido master et vidos pour. Télécharger iMovie est très simple et son caractère intuitif lui a valu tout son charme auprès des utilisateurs. You can turn off auto-renew at any time from your iTunes account settings but refunds will not be provided for any unused portion of the term. Formateur retouche Photoshop, expert Lightroom sur mac Formateur. As iOS hardware continues to become more powerful and get. Your Montage subscription will automatically renew at the end of each term and your credit card will be charged through your iTunes account. Theres no need to head to a Mac or PC to create a custom movie using photos, music, and video. Pricing in other countries may vary and actual charges may be converted to your local currency depending on the country of residence. ![]() These prices are for United States customers. Montage offers three auto-renewing subscription options: logiciel montage video Cette application permet de Logiciel interface pour mencoder et d’autres outils UNIX permettant d’encoder en Divx/h264 pour Mac Beauty hijab selfie camera is a trendy photo montage application. Accédez-y dans le cadre de la formule Tout Creative Cloud pour 62,47 /mois. For that reason Blender is Free and Open Source software, forever. Share with your friends on TikTok, Instagram, Facebook and more. Donnez vie à toutes vos idées avec les applications Adobe pour le montage vidéo, l’animation, les effets spéciaux et bien plus encore. public project hosted on, licensed as GNU GPL, owned by its contributors. Lumen5 is a video creation platform powered by AI that enables anyone without training or experience to easily create engaging video content within minutes. Combine your video clips together into one movie with Montage!Īdjust the length by quickly trimming out unwanted parts from your video.Ĭrop your movie to make it a perfect square. ![]() ![]() ![]() 7) Despite decades of searching around the world, the Japanese microorganism remains the only source of avermectin ever found. Promising bioactive samples were then sent to the MSD laboratories for further in vivo testing where a potent and promising novel bioactivity was found, subsequently identified as being caused by a new compound, which was named ‘avermectin’. Under the terms of the research agreement, researchers at the Kitasato Institute isolated organisms from soil samples and carried out preliminary in vitro evaluation of their bioactivity. In the early-1970s, a novel international Public Sector–Private Sector partnership was initiated by one of us (Ōmura, then head of the Antibiotics Research Group at Tokyo’s Kitasato Institute), forming a collaboration with the US-based Merck, Sharp and Dohme (MSD) pharmaceutical company. It was the world’s first endectocide, forerunner of a completely new class of antiparasitic agents, potently active against a wide range of internal and external nematodes and arthropods. ) was a truly revolutionary drug, unprecedented in many ways. When it first appeared in the late-1970s, ivermectin, a derivative of avermectin (Fig. 1– 6) However, none have concentrated in detail on the interacting sequence of events involved in the passage of the drug into human use. Several extensive reports, including reviews authored by us, have been published detailing the events behind the discovery, development and commercialization of the avermectins and ivermectin (22,23-dihydroavermectin B), as well as the donation of ivermectin and its use in combating Onchocerciasis and lymphatic filariasis. But ivermectin can also be considered alongside those worthy contenders, based on its versatility, safety and the beneficial impact that it has had, and continues to have, worldwide-especially on hundreds of millions of the world’s poorest people. ![]() There are few drugs that can seriously lay claim to the title of ‘Wonder drug’, penicillin and aspirin being two that have perhaps had greatest beneficial impact on the health and wellbeing of Mankind. This paper looks in depth at the events surrounding ivermectin’s passage from being a huge success in Animal Health into its widespread use in humans, a development which has led many to describe it as a “wonder” drug. It has also been used to successfully overcome several other human diseases and new uses for it are continually being found. It is now being used free-of-charge as the sole tool in campaigns to eliminate both diseases globally. It was quickly discovered to be ideal in combating two of the world’s most devastating and disfiguring diseases which have plagued the world’s poor throughout the tropics for centuries. Originally introduced as a veterinary drug, it kills a wide range of internal and external parasites in commercial livestock and companion animals. Discovered in the late-1970s, the pioneering drug ivermectin, a dihydro derivative of avermectin-originating solely from a single microorganism isolated at the Kitasato Intitute, Tokyo, Japan from Japanese soil-has had an immeasurably beneficial impact in improving the lives and welfare of billions of people throughout the world. ![]() |
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